Pharmacy Technician PTCB Practice Test

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What term is used to describe the situation where two drugs together result in an effect that is less than the effect of each drug alone?

Additive effect
Synergism
Potentiation
Antagonism

The correct answer is: Antagonism

Antagonism is the term used to describe the situation where two drugs together result in an effect that is less than the effect of each drug alone. In an antagonistic interaction, the drugs work in opposite directions or cancel out each other's effects, leading to a decreased overall effect. Let's briefly discuss the other options: A. Additive effect: This occurs when two drugs together result in an effect that is equal to the sum of the effects of each drug alone. B. Synergism: This occurs when two drugs together result in an effect that is greater than the sum of the effects of each drug alone. C. Potentiation: This occurs when one drug enhances the effect of another drug beyond what was expected based on the individual effects of each drug.