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What does potentiation refer to in pharmacology?

  1. Combination of 2 medications reducing the effect of each

  2. Combined effect of medications is equal to the individual effects

  3. Combination of 2 medications increasing the effect or length of effect

  4. The effect of one medication counteracts the effect of the other

The correct answer is: Combination of 2 medications increasing the effect or length of effect

Potentiation refers to the increased or prolonged effect of one medication when combined with another. This means that the combined effect of the two medications will be greater than the individual effects. Option A is incorrect because potentiation does not refer to a reduction in effect. Option B is incorrect because it implies that the combined effect is only equal to the individual effects. Option D is also incorrect because it describes an antagonist effect which is different from potentiation.